Dennis Hruby: search on Z-Library

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1

An overview of tecovirimat for smallpox treatment and expanded anti-orthopoxvirus applications

Russo, Andrew T., Grosenbach, Douglas W., Chinsangaram, Jarasvech, Honeychurch, Kady M., Long, Paul G, Lovejoy, Candace, Maiti, Biswajit, Meara, Ingrid, Hruby, Dennis E.

Journal:

Expert Review of Anti-infective Therapy

Year:

2020

File:

PDF, 1.17 MB

2020

2

Co-administration of tecovirimat and ACAM2000™ in non-human primates: Effect of tecovirimat treatment on ACAM2000 immunogenicity and efficacy versus lethal monkeypox virus challenge

Russo, Andrew T., Berhanu, Aklile, Bigger, Catherine B., Prigge, Jon, Silvera, Peter M., Grosenbach, Douglas W., Hruby, Dennis

Journal:

Year:

2019

Language:

english

File:

PDF, 1.60 MB

english, 2019

3

Oral Tecovirimat for the Treatment of Smallpox

Grosenbach, Douglas W., Honeychurch, Kady, Rose, Eric A., Chinsangaram, Jarasvech, Frimm, Annie, Maiti, Biswajit, Lovejoy, Candace, Meara, Ingrid, Long, Paul, Hruby, Dennis E.

Journal:

New England Journal of Medicine

Year:

2018

Language:

english

File:

PDF, 326 KB

english, 2018

4

Treatment with the Smallpox Antiviral Tecovirimat (ST-246) Alone or in Combination with ACAM2000 Vaccination Is Effective as a Postsymptomatic Therapy for Monkeypox Virus Infection

Berhanu, Aklile, Prigge, Jonathan T., Silvera, Peter M., Honeychurch, Kady M., Hruby, Dennis E., Grosenbach, Douglas W.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 986 KB

english, 2015

5

Metabolites of Glutamate Metabolism Are Associated With Incident Cardiovascular Events in the PREDIMED PREvención con DIeta MEDiterránea (PREDIMED) Trial

Zheng, Yan, Hu, Frank B., Ruiz‐Canela, Miguel, Clish, Clary B., Dennis, Courtney, Salas‐Salvado, Jordi, Hruby, Adela, Liang, Liming, Toledo, Estefania, Corella, Dolores, Ros, Emilio, Fitó, Montserrat,

Journal:

Journal of the American Heart Association

Year:

2016

Language:

english

File:

PDF, 1.01 MB

english, 2016

6

Discovery and development of antiviral drugs for biodefense: Experience of a small biotechnology company

Tove C. Bolken, Dennis E. Hruby

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 197 KB

english, 2008

7

Synthesis of oxytocin and related diastereomers deuterated in the half-cystine positions. Comparison of solid-phase and solution methods

Spatola, Arno F., Cornelius, Dennis A., Hruby, Victor J., Blomquist, Alfred T.

Journal:

Journal of Organic Chemistry

Year:

1974

Language:

english

File:

PDF, 866 KB

english, 1974

8

Development of the small-molecule antiviral ST-246 ® as a smallpox therapeutic

Grosenbach, Douglas W, Jordan, Robert, Hruby, Dennis E

Journal:

Future Virology

Year:

2011

Language:

english

File:

PDF, 2.27 MB

english, 2011

9

Development of ST-246® for Treatment of Poxvirus Infections

Jordan, Robert, Leeds, Janet M., Tyavanagimatt, Shanthakumar, Hruby, Dennis E.

Journal:

Year:

2010

Language:

english

File:

PDF, 428 KB

english, 2010

10

Plasma acylcarnitines and risk of cardiovascular disease: effect of Mediterranean diet interventions

Guasch-Ferre, M., Zheng, Y., Ruiz-Canela, M., Hruby, A., Martinez-Gonzalez, M. A., Clish, C. B., Corella, D., Estruch, R., Ros, E., Fito, M., Dennis, C., Morales-Gil, I. M., Aros, F., Fiol, M., Lapetr

Journal:

American Journal of Clinical Nutrition

Year:

2016

Language:

english

File:

PDF, 565 KB

english, 2016

11

Co-administration of tecovirimat and ACAM2000™ in non-human primates: Effect of tecovirimat treatment on ACAM2000 immunogenicity and efficacy versus lethal monkeypox virus challenge

Russo, Andrew T., Berhanu, Aklile, Bigger, Catherine B., Prigge, Jon, Silvera, Peter M., Grosenbach, Douglas W., Hruby, Dennis

Journal:

Year:

2019

File:

PDF, 1.60 MB

2019

12

Rifampicin prevents virosome localization of L65, an essential vaccinia virus polypeptide

Jeffrey N. Miner, Dennis E. Hruby

Journal:

Year:

1989

Language:

english

File:

PDF, 811 KB

english, 1989

13

Chlamydial development is blocked in host cells transfected withChlamydophila caviae incA

Damir Alzhanov, Jennifer Barnes, Dennis E Hruby, Daniel D Rockey

Journal:

BMC Microbiology

Year:

2004

Language:

english

File:

PDF, 1.98 MB

english, 2004

14

Importance of disulphide bonds for vaccinia virus L1R protein function

Robert E Blouch, Chelsea M Byrd, Dennis E Hruby

Journal:

Virology Journal

Year:

2005

Language:

english

File:

PDF, 174 KB

english, 2005

15

Structure and function of vaccinia virus thymidine kinase: Biomedical relevance and implications for antiviral drug design

Margaret E. Black, Dennis E. Hruby

Journal:

Reviews in Medical Virology

Year:

1991

Language:

english

File:

PDF, 1.15 MB

english, 1991

16

Small Molecule Inhibitors of Dengue Virus Replication are Active In Vivo

Chelsea Byrd, Chris Harver, Kara Cardwell, Doug Grosenbach, Aklile Berhanu, Dongcheng Dai, Dennis Hruby, Robert Jordan

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 84 KB

english, 2010

17

Synthesis of vaccinia virus thymidine kinase in microinjected Xenopus oocytes

Dennis E. Hruby, Donna B. Miller, L.Andrew Ball

Journal:

Year:

1982

Language:

english

File:

PDF, 371 KB

english, 1982

18

Expression vector pT7: TKII for the synthesis of authentic biologically active RNA encoding vaccinia virus thymidine kinase

Wilson, Elizabeth M., Franke, Christine A., Black, Margaret E., Hruby, Dennis E.

Journal:

Year:

1989

Language:

english

File:

PDF, 1.21 MB

english, 1989

19

Cell-free translation of a chimeric eucaryotic-procaryotic message yields functional chloramphenicol acetyltransferase

Walter M. Hodges, Dennis E. Hruby

Journal:

Analytical Biochemistry

Year:

1987

Language:

english

File:

PDF, 639 KB

english, 1987

20

Analysis of the Site Occupancy Constraints of Primary Amino Acid Sequences in the Motif Directing Palmitylation of the Vaccinia Virus 37-kDa Envelope Protein

Scott G. Hansen, Douglas W. Grosenbach, Dennis E. Hruby

Journal:

Year:

1999

Language:

english

File:

PDF, 364 KB

english, 1999

21

Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox – An animal model of smallpox

Scott Parker, Nanhai G. Chen, Scott Foster, Hollyce Hartzler, Ed Hembrador, Dennis Hruby, Robert Jordan, Randall Lanier, George Painter, Wesley Painter, John E. Sagartz, Jill Schriewer, R. Mark Buller

Journal:

Antiviral Research

Year:

2012

Language:

english

File:

PDF, 1013 KB

english, 2012

22

Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole

Dai, Dongcheng, Burgeson, James R., Gharaibeh, Dima N., Moore, Amy L., Larson, Ryan A., Cerruti, Natasha R., Amberg, Sean M., Bolken, Tove’ C., Hruby, Dennis E.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 2.33 MB

english, 2013

23

Viral acylproteins: greasing the wheels of assembly

Hruby, Dennis E., Franke, Christine A.

Journal:

Trends in Microbiology

Year:

1993

Language:

english

File:

PDF, 609 KB

english, 1993

24

Inhibition of vaccinia virus thymidine kinase by the Distal products of its own metabolic pathway

Hruby, Dennis E.

Journal:

Year:

1985

Language:

english

File:

PDF, 313 KB

english, 1985

25

[Methods in Enzymology] Recombinant DNA Part G Volume 216 || [32] Use of fluorescent chloramphenicol derivative as a substrate for chloramphenicol acetyltransferase assays

Hruby, Dennis E.

Year:

1992

Language:

english

File:

PDF, 806 KB

english, 1992

26

Vaccinia and cowpox viruses encode a novel secreted interleukin-1-binding protein

Melanie K. Spriggs, Dennis E. Hruby, Charies R. Maliszewski, David J. Pickup, John E. Sims, R.Mark L. Buller, Judy VanSlyke

Journal:

Year:

1992

Language:

english

File:

PDF, 1.10 MB

english, 1992

27

Commensal bacteria as a novel delivery system for subunit vaccines directed against agents of bioterrorism

Rebecca L. Wilson, Dennis E. Hruby

Journal:

Advanced Drug Delivery Reviews

Year:

2005

Language:

english

File:

PDF, 530 KB

english, 2005

28

Successful Treatment in the Monkeypox and Variola Primate Models of Smallpox by the Oral Drug ST-246

John Huggins, Arthur Goff, Mucker Eric, Nancy Twenhafel, Jennifer Chapman, Mallory Tate, Rob Jordan, Tove’ Bolken, Dennis Hruby

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 65 KB

english, 2007

29

Smallpox antiviral drug development: satisfying the animal efficacy rule

Jordan, Robert, Hruby, Dennis

Journal:

Expert Review of Anti-infective Therapy

Year:

2006

Language:

english

File:

PDF, 272 KB

english, 2006

30

Biology of vaccinia virus acylproteins

Hruby, Dennis E

Journal:

Frontiers in Bioscience

Year:

1998

Language:

english

File:

PDF, 335 KB

english, 1998

31

The multistep proteolytic maturation pathway utilized by vaccinia virus P4a protein: A degenerate conserved cleavage motif within core proteins

Judy K. Vanslyke, Stephen S. Whitehead, Elizabeth M. Wilson, Dennis E. Hruby

Journal:

Year:

1991

Language:

english

File:

PDF, 1.87 MB

english, 1991

32

Discovery of Novel Small Molecule Inhibitors of Dengue Virus Replication

Chelsea Byrd, Eric Stavale, Andrews Wieczorek, Thaun Tran, Dennis Hruby, Robert Jordan

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 62 KB

english, 2007

33

Novel Small Molecule Inhibitors of Dengue Virus Replication

Chelsea Byrd, Jessica Page, Chris Harver, Doug Grosenbach, Aklile Berhanu, Dennis Hruby, Robert Jordan

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 69 KB

english, 2009

34

BiZyme: A Novel Fusion Protein-Mediating Selection of Vaccinia Virus Recombinants by Fluorescence and Antibiotic Resistance

Hansen, Scott G., Cope, Torrey A., Hruby, Dennis E.

Journal:

Year:

2002

File:

PDF, 332 KB

2002

35

Evidence for multiple species of vaccinia virus-encoded palmitylated proteins

Stephanie J. Child, Dennis E. Hruby

Journal:

Year:

1992

Language:

english

File:

PDF, 2.17 MB

english, 1992

36

ST-246, a Therapeutic for Smallpox

Tahar Babas, Deborah Sites, Lourdes Nieves-Duran, Amy Sands, Rhonda Wright, Amy Rippeon, Dawn Golightly, Ginger Donnelly, Lowrey Rhodes, Robert Jordan, Dennis Hruby, Peter Silvera

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 68 KB

english, 2010

37

SAR analysis of a series of acylthiourea derivatives possessing broad-spectrum antiviral activity

James R. Burgeson, Amy L. Moore, Jordan K. Boutilier, Natasha R. Cerruti, Dima N. Gharaibeh, Candace E. Lovejoy, Sean M. Amberg, Dennis E. Hruby, Shanthakumar R. Tyavanagimatt, Robert D. Allen III, Do

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 3.24 MB

english, 2012

38

A tandemly–oriented late gene cluster within the vaccinia virus genome

Weinrich, Scott L., Hruby, Dennis E.

Journal:

Nucleic Acids Research

Year:

1986

Language:

english

File:

PDF, 1016 KB

english, 1986

39

Present and future applications of vaccinia virus as a vector

Dennis E. Hruby

Journal:

Veterinary Parasitology

Year:

1988

Language:

english

File:

PDF, 637 KB

english, 1988

40

Establishment of a Cell-based HTS System for Discovery of Anti-Flavivirus Drugs

Yali Chen, Chris Harver, Travis Warren, Dennis Hruby, Robert Jordan

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 66 KB

english, 2008

41

Conditional expression of vaccinia virus genes in mammalian cell lines expressing the tetracycline repressor

Marika Hedengren-Olcott, Dennis E Hruby

Journal:

Journal of Virological Methods

Year:

2004

Language:

english

File:

PDF, 180 KB

english, 2004

42

Nucleotide sequence and molecular genetic analysis of the large subunit of ribonucleotide reductase encoded by vaccinia virus

Leslie A. Tengelsen, Mary B. Slabaugh, Jody K. Bibler, Dennis E. Hruby

Journal:

Year:

1988

Language:

english

File:

PDF, 3.68 MB

english, 1988

43

Construction of a recombinant vaccinia virus which expresses immunoreactive plant virus proteins

William G. Dougherty, Christine A. Franke, Dennis E. Hruby

Journal:

Year:

1986

Language:

english

File:

PDF, 1.24 MB

english, 1986

44

Development of anin vitrocleavage assay system to examine vaccinia virus I7L cysteine proteinase activity

Chelsea M Byrd, Dennis E Hruby

Journal:

Virology Journal

Year:

2005

Language:

english

File:

PDF, 805 KB

english, 2005

45

Uses of vaccinia virus in vaccine delivery

David Ulaeto, Dennis E Hruby

Journal:

Current Opinion in Biotechnology

Year:

1994

Language:

english

File:

PDF, 447 KB

english, 1994

46

Nucleotide sequence and transcriptional studies of the vaccinia virusKpnI I DNA fragment

Leslie A. Tengelsen, Dennis E. Hruby

Journal:

Year:

1989

Language:

english

File:

PDF, 1.03 MB

english, 1989

47

Evaluation of orally delivered ST-246 as postexposure prophylactic and antiviral therapeutic in an aerosolized rabbitpox rabbit model

Aysegul Nalca, Josh M. Hatkin, Nicole L. Garza, Donald K. Nichols, Sarah W. Norris, Dennis E. Hruby, Robert Jordan

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 1.36 MB

english, 2008

48

Characterization of a binding factor that interacts with the sequences upstream of the vaccinia virus thymidine kinase gene

Elizabeth M. Wilson, Cheryl Edbauer, Dennis E. Hruby

Journal:

Year:

1988

Language:

english

File:

PDF, 2.47 MB

english, 1988

49

Identification and Analysis of Vaccinia Virus Palmitylproteins

Douglas W. Grosenbach, Scott G. Hansen, Dennis E. Hruby

Journal:

Year:

2000

Language:

english

File:

PDF, 355 KB

english, 2000

50

Novel codon utilization within the vaccinia virus thymidine kinase gene

Hruby, Dennis E., Guarino, Linda A.

Journal:

Year:

1984

Language:

english

File:

PDF, 409 KB

english, 1984

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